|Manga Debut||The Heart of a Fire Soldier|
The Powder Medicine (粉薬, Konagusuri) is a powdered substance, which was referred to by Tamaki to be a some sort of sand-like powder. It can be used to induce explosions, powerful enough to force a building's ceiling to collapse, and was given to Joker by a mysterious scientist. The substance is contained in a bottle, which appears to keep it inactive. Its main components are the ashes of Flame Humans.